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徐效华   教授 博士生导师 

Prof. Xiao-Hua Xu (X.-H. Xu )

Tel: 86-22-23508871

E-mail: xiaohuaxu @nankai.edu.cn 

 

EDUCATION

1995-1997              Institute of Elemento-organic Chemistry, Nankai University, Tianjin,
          CHINA.
Postdoctoral associat (with Prof. Ru-Yu Chen)

1992-1995              Department of Chemistry, Zhongshan University Received Ph.D.
          degree in June, 1995 (with Prof. Jing-Yu Su
)

1987-1990              Institute of Elemento-organic ChemistryNankai University,  
          Tianjin,
CHINA
Received M.S.degree in June, 1995 (with Prof.
          Qing-lan
Xie)

1983-1987              Department of Chemistry, Anhui Normal University, Wu hu,
          CHINA. Recei
ved B. Sc. Degree in June, 1990

 

ACADEMIC CAREER

2002-2014
Vice Director, Institute of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA.
2002- 
Professor, Institute of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA.
2002-
Postdoctoral associate, Chinese University of HongKong (with Prof. Henry N. C. WONG).
1997-2002
Associate Professor, Institute of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA.

RESEARCH AREAS

 

(1) Natural products. especially ecological function natural products 

(2) Design and synthesis of Agrochemicals

(3) Plant Allelopathy

 

HONORS AND AWARDS

2008   Award for china society of plant protection             

 

SELECTED PUBLICATIONS

  1. Yang Liu, Kang Lei, Na Liu, Dong-Wei Sun, Xue-Wen Hua , Ya-Juan Li and Xiao-Hua Xu* Indium-Mediated Intramolecular Reaction of N-2-Iodobenzoyl)-azabenzonorbornadienes: A General Access to Dihydrobenzo[c]phenanthridinones  J. Org. Chem. 2016, 81, 5495−5503 

  2. Kang Lei, Dong-wei Sun, Xue-wen Hua, Yuan-yuan Tao, Xiao-hua Xu*, Chui-hua Kong. Synthesis, Fungicidal Activity, and Structure–Activity Relationships of 3-Benzoyl-4-Hydroxylcoumarin Derivatives. Pest Manag. Sci. 2016,72,172–178

  3. Kang LeiXue-wen Hua, Yuan-yuan Tao, Yang Liu, Na Liu, Yi Ma, Yong-hong Li, Xiao-hua Xu, Chui-hua Kong. Discovery of (2-Benzoylethen-1-ol)-Containing 1,2-Benzothiazine Derivatives as Novel 4-Hydroxyphenylpyruvate Dioxygenase (HPPD) Inhibiting-Based Herbicide Lead Compounds.  Bioorg. Med. Chem. 201624, 92–103.

  4. CuiGuo, Dong-WeiSun, Suang Yang, Shen-Jie Mao, Xiao-Hua Xu,* Shou-Fei Zhu,* and Qi-Lin Zhou* Iridium-Catalyzed Asymmetric Hydrogenation of 2Pyridyl Cyclic Imines: A Highly Enantioselective Approach to Nicotine Derivatives  J. Am. Chem. Soc. 2015, 137, 90−93.

  5. Fu-Hai Zhang, Yang Liu,  Long-Guan Xie and Xiao-Hua Xu   Diastereoselection during 1,2-addition of 3-bromomethyl-5H-furan-2-one to α-   chiral aldehydes mediated by indium in aqueous and organic solvent systems: Direct route to obtain opticallyα-methylene-γ-butyrolactones.  RSCAdvances 2014,4,17218.

  6. Cui Guo, Kang-Lun Huang, Long-Guan Xie,  Xiao-Hua Xu* Pd-catalyzed annulation reactions of methyl-o-halobenzoates with azabicyclic alkenes: a general protocol for the construction of benzo[c]phenanthridine derivatives RSC Advances 2013, 3, 17271–17280.

  7. Fu-Hai Zhang, Yan-Xin Yang, Long-Guan.Xie  Xiao-Hua.Xu* Pd-catalyzed diastereoselectiveallylation of aldehydes with 3-bromomethyl-5H-furan-2-one: stereoselective synthesis of β-(hydroxymethylaryl/alkyl-α-methylenec-butyrolactones with a synconfiguration  Chem. Commun., 201349, 4697—4699.

  8. Kang-Lun Huang, Cui Guo, Long-Guan Xie, Qi-Lin Zhou, Xiao-Hua Xu* and Shou-Fei Zhu* Enantioselective Palladium-Catalyzed Ring-Opening Reaction of Azabenzonorbornadienes with Methyl 2-Iodobenzoate: An Efficient Access to cis-Dihydrobenzo [c]phenanthridinones    Adv. Synth. Catal., 2013,355, 2833 – 2838.

  9. Min ZhangXiao-Hua Xu* and Chui-hua Kong Synthesis and Herbicidal Potential of Substituted Aurones  Pest Manag. Sci2012,68,1512-1522.

  10. Yu-Zhe. GaoXue WangLi-Dong. SunLong-Guan.Xie , Xiao-Hua Xu*  Zinc and indium-mediated Barbier-type allylation of aldehydes with 3-bromomethyl-5H-furan-2-one: an efficient synthesis of α-methylene-γ-butyrolacton Org. Biomol. Chem., 2012, 10, 3991-3998.

  11. Hai-Sheng Yang, Yu-Zhe Gao, Xiao-Xiao Qiao, Long-Guan Xie, and Xiao-Hua Xu*  Concise Total Synthesis of (−)-8-Epigrosheimin  Org. Lett.2011,13(14), 3670–3673.

  12. Pei Lv, Kang-Lun Huang, Long-Guan Xie and Xiao-Hua XuPalladium-Catalyzed Tandem Reaction to Construct Benzo[c] phenanthridine: Application to the Total Synthesis of Benzo[c] phenanthridine alkaloids  Org. Biomol. Chem.2011, 9, 3133-3135.

 

 

 

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