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Palladium-Catalyzed Amide-Directed Enantioselective Hydrocarbofunctionalization of Unactivated Alkenes Using a Chiral Monodentate Oxazoline Ligand. Hao Wang, Zibo Bai, Tangqian Jiao, Zhiqiang Deng, Huarong Tong, Gang He*, Qian Peng*, and Gong Chen* J. Am. Chem. Soc. 2018, asap, DOI: 10.1021/jacs.8b00641.
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General Strategy for Synthesis of Cyclophane-Braced Peptide Macrocycles via Palladium-Catalyzed Intramolecular sp3 C−H Arylation. Xuekai Zhang, Gang Lu, Meng Sun, Madhu Mahankali, Yanfei Ma, Mingming Zhang, Wangde Hua, Yuting Hu, Qingbing Wang, Jinghuo Chen, Gang He*, Xiangbing Qi*, Weijun Shen*, Peng Liu* and Gong Chen*. Nature Chem. 2018, accepted.
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An Enantioselective Bidentate Auxiliary Directed Palladium- Catalyzed Benzylic C H Arylation of Amines Using a BINOL Phosphate Ligand. Hao Wang, Hua-Rong Tong, Gang He*, and Gong Chen*. Angew. Chem., Int. Ed. 2016, 55, 15387-15391.
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Benzazetidine Synthesis via Palladium-Catalyzed Intramolecular C−H Amination. Gang He,* Gang Lu, Zhengwei Guo, Peng Liu,* and Gong Chen*. Nature Chem. 2016, 8, 1131-1136.
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Total Synthesis of Mannopeptimycins and α and β. Bo Wang, Yunpeng Liu, Rui Jiao, Yiqing Feng, Qiong Li, Chen Chen, Long Liu, Gang He, and Gong Chen*. J. Am. Chem. Soc. 2016, 138, 3926-3932, DOI: 10.1021/jacs.6b01384
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Pd-catalyzed Mono-selective ortho-C−H Alkylation of N-Quinolyl Benzamides: Evidence for Stereo-retentive Coupling of Secondary Alkyl Iodides. Shuyu Zhang, Qiong Li, Gang He, William A. Nack, and Gong Chen*. J. Am. Chem. Soc. 2015, 137, 531-539.
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Stereoselective Synthesis of β-Alkylated α-Amino Acids via Palladium-Catalyzed Alkylation of Methylene C(sp3)−H Bonds. Shu-Yu Zhang, Qiong Li, Gang He, William A. Nack, and Gong Chen*. J. Am. Chem. Soc. 2013, 135, 12135−12141.
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Use of a Readily Removable Auxiliary Group for the Synthesis of Pyrrolidones by the Palladium-Catalyzed Intramolecular Amination of Unactivated C(sp3)−H Bonds. Gang He, Shu-Yu Zhang, William A. Nack, and Gong Chen*. Angew. Chem., Int. Ed. 2013, 52, 11124−11128.
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Palladium-Catalyzed Picolinamide-Directed Alkylation of Unactivated C(sp3)−H Bonds with Alkyl Iodides. Shuyu Zhang, Gang He, William A. Nack, Yingsheng Zhao, Qiong Li, and Gong Chen*. J. Am. Chem. Soc. 2013, 135, 2124−2127.
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Efficient Ether Synthesis via Palladium-catalyzed Picolinamide-directed Alkoxylation of Unactivated C(sp3) and C(sp2)−H Bonds at Remote Positions. Shuyu Zhang, Gang He, Yingsheng Zhao, and Gong Chen*. J. Am. Chem. Soc. 2012, 134, 7313−7316.